Transcriptional and Epigenetic Mechanisms of Neuronal Plasticity

Angel Barco Laboratory

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Angel Barco studied Biology at the Universidad de Extremadura and Universidad Autónoma de Madrid. He got his Master thesis and Ph.D. degree in the Centro de Biología Molecular "Severo Ochoa" (UAM, Madrid) working on the mechanism of citotoxicity and regulation of gene expression by poliovirus under the supervision of Dr. Carrasco. Because of his interest in Neurosciences, particularly on the molecular mechanisms of cognition and the genetic bases of behavior, he joined in 1998 the group of Nobel Laureate Dr. Kandel at Columbia University to work on the molecular bases of learning and memory. His research there focused on the role of the cAMP-responsive element binding protein (CREB) family of transcription factors in synaptic plasticity and memory. In September 2004, he moved to the Instituto de Neurociencias (UMH-CSIC) in Alicante, where he established his own laboratory thanks to the support of the European Commission through the now extinct Marie Curie Excellence Grant Programme. Here, his group applies a multidisciplinary approach to investigate the role of transcriptional and epigenetic regulation of gene expression in neuronal plasticity, learning and memory, and neuropsychiatric diseases. He now has a permanent position as CSIC Research Investigator.

See publications by Angel Barco

Luismi
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Luis M. Valor studied Biology at the Universidad de Alicante and got his Ph.D. under the supervision of Dr. Manuel Criado in the Universidad Miguel Hernández. The subject of his Thesis was the identification of the transcriptional elements involved on the basal expression of neural nicotinic acetylcholine receptor subunits. For his postdoc, he moved to the laboratory of Prof. Seth G.N. Grant in The Wellcome Trust Sanger Institute (Hinxton, Cambridge, UK) to undertake genome-wide approaches to study synaptogenesis, neural stimulation and knockouts of synaptic plasticity proteins. He currently has a Ramón y Cajal contract.

See publications by Luis M Valor


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José P. López-Atalaya studied Biology and Biochemistry at the Universidad de Murcia (UM). He worked as an intern student in the Group of Biochemistry and Enzymatic Biotechnology at the Department of Biochemistry and Molecular Biology. In 2002, he moved to GIP CYCERON in France where he carried out his Master thesis and his doctoral thesis at Inserm U919 under the supervision of Prof. Dr. Denis Vivien working in the role of tissue-plasminogen activator in glutamatergic neurotransmission and neurodegeneration caused by acute ischemic stroke. He joined our lab moved by his interest in studying the molecular mechanisms of learning and memory.

See publications by Jose Lopez-Atalaya

Beatriz
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Beatriz del Blanco studied Biochemistry at the Universidad de Granada. She carried out her Master and PhD thesis with PhD. Cristina Hernández Munain at Instituto de Parasitología y Biomedicina “López Neyra” (CSIC) in Granada. Her research has focused on studying the transcriptional and epigenetic mechanisms involved in regulation of gene expression during T-lymphocytes development. In 2010, she collaborated with Michael S. Krangel´s Lab in the Duke University through a short term stay. In June 2014, she joined our lab moved by her interest in studying epigenetic regulation in neuronal plasticity.

Valentina
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Deisy Guiretti estudied Biology at the National University of Misiones, Argentina. She later investigated in the field of viral variability and phylogenia at the National Institute of Cancer in Rio de Janeiro and in the University of Edinburgh. She joined our lab to carry out her thesis working on the etiology of Huntington's disease.
Anna
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Anna Fiorenza studied Biology at the Università degli studi del Sannio in Italy. In 2008, she moved to the Instituto de Neurociencias de Alicante, as part of the "Erasmus Placement" subprogram in the U.E. Lifelong Learning Programme, where she worked in the lab of Dr. Lerma in the physiology of kainate receptors. She was awarded a fellowship from the INA-Consolider Program and decided to join our group to carry out her thesis.
Anna
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Marilyn Scandaglia studied Molecular Biotechnology at the Università Alma Mater Studiorum di Bologna in Italy. In 2011, as a pregraduate student, she moved to the Instituto de Neurociencias de Alicante and joined our lab to carry out her Master thesis. She currently has a FPI fellowship.
Anna
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Michal Lipinski studied Biotechnology at the Warsaw University of Life Sciences (Poland) and was initially trained on Neurosciences in laboratories at the Nencki Institute of Experimental Biology (Warsaw) and the Neural Basis of Behaviour Division in the University of Zurich. In June 2012, he joined our group thanks to a fellowship awarded by the Santiago Grisolia Program financed by the Generalitat Valenciana.
Alejandro
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Alejandro Medrano studied Criminolology at the Universidad de Alicante. He is now coordinating his studies in Psycology at UNED with the Neuroscience Master in our Institute. After a short stay in our lab as a summer student, he decided to join our group to carry out his Master thesis with us.

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Román Olivares got his qualification as technician in Madrid, and worked for several years in the laboratory of Dr. Garcia (Department of Pharmacology of the Universidad Autónoma de Madrid). There, he investigated secretion by chromaffin cells and importantly contributed to a number of international publications. He has been responsible of our colony of knockout and transgenic mice and the general organization of the lab since the creation of our research group in 2004.
 

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