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People About the institute Laura Almaraz Gómez
Degree:
MD (1980), University of Valladolid.

Ph.D program:
PhD (1983), University of Valladolid.

Posdoctoral Positions:
Department of Physiology. School of Medicine. University of Utah Salt Lake City (USA). 1984 - 1986.

Previous positions:
Assistant Professor of Physiology.  Department of Biochemistry and Molecular Biology and Physiology, University of Valladolid.
Researcher,  IBGM (CSIC - University of Valladolid)

Current Position:
Assistant Professor of Physiology.  Departamento de Fisiología, Universidad Miguel Hernández.

Research Fields:
1. Physiology of the carotid body type I cells; These are quimiorreceptor cells sensitive to the O2 and CO2 partial pressure and to the blood pH. We use current and membrane potential recordings with patch electrodes from dissociated cells from the carotid body kept in primary cultures. The main lines of work are the study of:

a. The calcium currents present in the cell membrane and their role in the secretion of catecholamines.
b. The effect of natural stimuli and of several metabolic venoms on the electrical responses of these cells.


2. The basic physiological mechanisms of the cortical local circuits, and in particular of the prefrontal cortex circuits.

Representative Publications

Pérez-García, M.T. , Almaraz, L., González, C. " Effects of different types of stimulation on cyclic AMP content in the rabbit carotid body: Functional significance. " J. Neurochem. . 55 , 1287 - 1293 ( 1990 )

Gómez-Niño, A. , López-López, J.R., Almaraz, L., González, C. " Inhibition of 3H-catecholamine release and Ca2+ currents by prostaglandine E2 in rabbit carotid body chemoreceptor cells”. " J. Physiol. . 476 , 269 - 277 ( 1994 )

Gonzalez, C. , Almaraz, L., Obeso, R., Rigual, R. " Carotid body chemoreceptors: From natural stimuli to sensory discharges”. " Physiol. Rev. . 74 , 829 - 877 ( 1994 )

Rocher, A. , González, C., Almaraz, C. " Adenosine inhibits L-type calcium channels and catecholamine release from chemoreceptor cells of rabbit carotid body”. " Eur. J. Neurosci . 11 , 673 - 681 ( 1999 )

Rigual, R. , Almaraz, L., Gonzalez, C., Donnelly, D. " Developmental changes in chemoreceptor nerve activity and catecholamine secretion in rabbit carotid body: possible role of Na+ and Ca2+currents. " Pflügers Arch. Eur. J. Physiol . 493 , 463 - 470 ( 2000 )
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